Regression of metastatic carcinoid tumor after valvular surgery for carcinoid heart disease

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Valvular Disorders in Carcinoid Heart Disease

Carcinoid heart disease is a rare but important cause of intrinsic right heart valve disorders leading to right heart failure. Occasionally, left-sided heart valves may also be involved. The characteristic cardiac pathological findings of carcinoid heart disease are endocardial thickening as a result of fibrous deposits on the endocardium. Echocardiographic examination and right heart catheteri...

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Cardiac surgery for carcinoid heart disease.

Carcinoid is a rare tumor originating from neuroendocrine cells, which are generally localized in the gastrointestinal tract. It has an annual incidence of 1.5 persons per 100 000. Usually, only carcinoid tumors that invade the liver result in pathological changes to the heart. The cardiac manifestations are caused by paraneoplastic effects of vasoactive substances such as serotonin, bradykinin...

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In recent years there has been a great deal of interest in the so-called carcinoid syndrome. This syndrome has been observed in many cases of carcinoid tumour of the gastro-intestinal tract with extensive metastasis. It consists of certain transient and permanent vaso-motor changes, bronchoconstriction, hyperperistalsis, oedema and ascites, pellagra, and mural and valvular endocardial sclerosis...

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ژورنال

عنوان ژورنال: Cancer

سال: 1997

ISSN: 0008-543X,1097-0142

DOI: 10.1002/(sici)1097-0142(19970201)79:3<605::aid-cncr25>3.3.co;2-k